Searchable abstracts of presentations at key conferences in endocrinology

ea0022p526 | Male reproduction | ECE2010

Effects of atorvastatin on male fertility

Pons-Rejraji Hanae , Sion Benoit , Brugnon Florence , Artonne Christine , Gouby Gerald , Grizard Genevieve , Janny Laurent , Tauveron Igor

Introduction: Dyslipidemia and impaired fertility are highly related. In animals, statin intake reduces sperm parameters deterioration associated with hypercholesterolemia. However, statin effects on human fertility are controversial. Their intake by hypercholesterolemic patients could reduce circulating testosterone concentration and sperm quality. While recommendations for cardiovascular prevention advocate lowering total cholesterol and LDL-C, atorvastatin, the most prescri...